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In cases of asthma or lung inflammation, there have been three studies confirming the effectiveness of Hemlock Varnish Shelf. It's been found to "exert anti-inflammatory effects on airway responses" in cases of allergic asthma and broncheoalveolar inflammation. Commercially cultivated in Taiwan and exported to mainland China as a medicinal mushroom, Hemlock Reishi has traditionally been used in Chinese medicine to treat inflammatory diseases, particularly asthma and autoimmune conditions. One of the most novel uses of Hemlock Varnish Shelf is as a skin substitute during wound healing. The skin substitute material, commercially sold as Sacchachitin, has been proven in numerous studies to promote and speed up skin healing. It has been observed that "rapid wound healing" takes place when covered by Sacchachitin as compared to regular gauze. Cap: 5-30 cm; at first irregularly knobby or elongated, but by maturity more or less fan-shaped; with a shiny, varnished surface often roughly arranged into lumpy "zones"; red to reddish brown when mature; when young often with zones of bright yellow and white toward the margin; occasionally with bluish tints.

Ecology: Saprobic on decaying conifer logs and stumps (especially hemlock wood); growing alone or in groups; annual; producing "a soft wet whitish or straw-colored cellulose-destroying decay of the wood" when young, and later a "network of cracks filled with white mycelium" with "numerous black dots throughout the wood" widely distributed in North America.

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Pore Surface: White, becoming dingy brownish in age; usually bruising brown; 4-6 tiny (nearly invisible to the naked eye) circular pores per mm; tubes to 2 cm deep. As with the Common Reishi, Hemlock Varnish Shelf extract appears to be immunomodulatory - meaning that it will adjust the immune system up or down depending on what is needed. It helps strengthen a weak immune system, but will calm an over-active immune system in cases of inflammation or autoimmune conditions. It also appears quite clear that Hemlock Varnish Shelf extract contains an abundance of antioxidants. A study from 1999 found Hemlock Varnish Shelf extract to possess "the strongest antioxidant activity of five species of Ganoderma tested," stronger than Vitamin E.

Microscopic Features: Spores 9-11 x 6-8; more or less elliptical, sometimes with a truncated end; usually appearing roughened even at lower magnifications. The single study conducted on Hemlock Varnish Shelf extract to treat an autoimmune disease, conducted in 2001, concluded that it "improved the survival rate of lupus." As with the Common Reishi, Hemlock Varnish Shelf extract appears to be immunomodulatory - meaning that it will adjust the immune system up or down depending on what is needed. It helps strengthen a weak immune system, but will calm an over-active immune system in cases of inflammation or autoimmune conditions. Like G. lucidum, G. tsugae is said to have medicinal properties.