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Phylogenetic analysis of ganodermahas begun to better differentiate between many closely related species of ganoderma; Hemlock Varnish Shelf is not limited to the U.S., though, and plenty of Asian research has been conducted specifically on this species of Reishi. As with the Common Reishi, Hemlock Varnish Shelf extract appears to be immunomodulatory - meaning that it will adjust the immune system up or down depending on what is needed. It helps strengthen a weak immune system, but will calm an over-active immune system in cases of inflammation or autoimmune conditions.

Stem: Sometimes absent, but more commonly present; 3-14 cm long; up to 3 cm thick; twisted; equal or irregular; varnished and colored like the cap; often distinctively angled away from one side of the cap. Much of the therapeutic benefits are the same as those of the Common Reishi (ganoderma lucidum), which is the oldest used medicinal mushroom in Traditional Chinese Medicine with a 2,000 year history. Spore Print: Brown. In the case of extracting the polysaccharides in ganoderma tsugae, a hot water extraction or tea can be very effective; however, to best extract the triterpenoids present in G. tsugae it is best to use an alcohol or alcohol/glycerin extraction method. This mushroom is closely related to ganoderma lucidum and is virtually indistinguishable from that species. However, ganoderma tsugae is partial to conifers--especially hemlock.

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Polyporus tsugae is a former name. Hemlock Varnish Shelf (ganoderma tsugae) is the local variety of Reishi for eastern United States. It is common on Hemlock trees throughout the Appalachian range. Like ganoderma lucidum, ganoderma tsugae is non-poisonous but generally considered inedible, due to its solid woody nature; however, making ganoderma teas and extacts from its fruiting bodies is an excellent way make use of the medicinal compounds present in ganoderma tsugae. The study applied several DNA techniques and found that, while ganoderma tsugae and ganoderma lucidum do appear to separate with some methods, the picture is unclear enough that further study is required before reliable conclusions can be drawn.

Hemlock Varnish Shelf is not limited to the U.S., though, and plenty of Asian research has been conducted specifically on this species of Reishi. Commercially cultivated in Taiwan and exported to mainland China as a medicinal mushroom, Hemlock Reishi has traditionally been used in Chinese medicine to treat inflammatory diseases, particularly asthma and autoimmune conditions. ganoderma lucidum is found on hardwood stumps and logs (very rarely on conifers), and has brownish flesh. ganoderma oregonense is a conifer lover of the Pacific Northwest and New Mexico; it has larger spores and a much larger fruiting body (up to one meter across!).