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With ganoderma there is still an ongoing scientific debate as to which species of ganoderma have the most medicinal properties. A 1995 DNA study of ganoderma (Moncalvo, Wang & Hseu) found that worldwide collections of ganoderma tsugae may not be genetically compatible. Spore Print: Brown.

A 1995 DNA study of ganoderma (Moncalvo, Wang & Hseu) found that worldwide collections of ganoderma tsugae may not be genetically compatible. Additionally, it has whitish, rather than brownish flesh. Otherwise it is recognized, like ganoderma lucidum, by its varnished, reddish cap and stem. The single study conducted on Hemlock Varnish Shelf extract to treat an autoimmune disease, conducted in 2001, concluded that it "improved the survival rate of lupus."

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The study applied several DNA techniques and found that, while ganoderma tsugae and ganoderma lucidum do appear to separate with some methods, the picture is unclear enough that further study is required before reliable conclusions can be drawn. A "wound area covered by SACCHACHITIN completely healed by 21 days, while that covered with cotton gauze did not." Polyporus tsugae is a former name. In cases of asthma or lung inflammation, there have been three studies confirming the effectiveness of Hemlock Varnish Shelf. It's been found to "exert anti-inflammatory effects on airway responses" in cases of allergic asthma and broncheoalveolar inflammation.

Like ganoderma lucidum, ganoderma tsugae is non-poisonous but generally considered inedible, due to its solid woody nature; however, making ganoderma teas and extacts from its fruiting bodies is an excellent way make use of the medicinal compounds present in ganoderma tsugae.