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Variations of ganoderma within the same species as well as the growth substrate and environmental conditions all the way through to preparation of the ganoderma tea or extract can have a substantial effect on the medicinal value of the product.

The single study conducted on Hemlock Varnish Shelf extract to treat an autoimmune disease, conducted in 2001, concluded that it "improved the survival rate of lupus." One study conducted in 2004 found Hemlock Varnish Shelf extract to posses liver protective properties and be anti-fibrotic.

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Spore Print: Brown. Ecology: Saprobic on decaying conifer logs and stumps (especially hemlock wood); growing alone or in groups; annual; producing "a soft wet whitish or straw-colored cellulose-destroying decay of the wood" when young, and later a "network of cracks filled with white mycelium" with "numerous black dots throughout the wood" widely distributed in North America. Variations of ganoderma within the same species as well as the growth substrate and environmental conditions all the way through to preparation of the ganoderma tea or extract can have a substantial effect on the medicinal value of the product.

Phylogenetic analysis of ganodermahas begun to better differentiate between many closely related species of ganoderma; Spore Print: Brown.

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