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With ganoderma there is still an ongoing scientific debate as to which species of ganoderma have the most medicinal properties. Hemlock Varnish Shelf extract has also been tested for its antitumor properties with promising results. In particular lung cancer and breast cancer 816have responded favorably in scientific research. It was also shown in one study to help prevent cancer metastasis. One study conducted in 2004 found Hemlock Varnish Shelf extract to posses liver protective properties and be anti-fibrotic.

Stem: Sometimes absent, but more commonly present; 3-14 cm long; up to 3 cm thick; twisted; equal or irregular; varnished and colored like the cap; often distinctively angled away from one side of the cap. Hemlock Varnish Shelf is not limited to the U.S., though, and plenty of Asian research has been conducted specifically on this species of Reishi.

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One study conducted in 2004 found Hemlock Varnish Shelf extract to posses liver protective properties and be anti-fibrotic. This mushroom is closely related to ganoderma lucidum and is virtually indistinguishable from that species. However, ganoderma tsugae is partial to conifers--especially hemlock. A 1995 DNA study of ganoderma (Moncalvo, Wang & Hseu) found that worldwide collections of ganoderma tsugae may not be genetically compatible. The study applied several DNA techniques and found that, while ganoderma tsugae and ganoderma lucidum do appear to separate with some methods, the picture is unclear enough that further study is required before reliable conclusions can be drawn. Ecology: Saprobic on decaying conifer logs and stumps (especially hemlock wood); growing alone or in groups; annual; producing "a soft wet whitish or straw-colored cellulose-destroying decay of the wood" when young, and later a "network of cracks filled with white mycelium" with "numerous black dots throughout the wood" widely distributed in North America.

Microscopic Features: Spores 9-11 x 6-8; more or less elliptical, sometimes with a truncated end; usually appearing roughened even at lower magnifications. ganoderma tsugae, also known as Hemlock varnish shelf, is a flat polypore mushroom of the genus ganoderma. Commercially cultivated in Taiwan and exported to mainland China as a medicinal mushroom, Hemlock Reishi has traditionally been used in Chinese medicine to treat inflammatory diseases, particularly asthma and autoimmune conditions.