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The single study conducted on Hemlock Varnish Shelf extract to treat an autoimmune disease, conducted in 2001, concluded that it "improved the survival rate of lupus." Like G. lucidum, G. tsugae is said to have medicinal properties. Variations of ganoderma within the same species as well as the growth substrate and environmental conditions all the way through to preparation of the ganoderma tea or extract can have a substantial effect on the medicinal value of the product.

One study conducted in 2004 found Hemlock Varnish Shelf extract to posses liver protective properties and be anti-fibrotic. In cases of asthma or lung inflammation, there have been three studies confirming the effectiveness of Hemlock Varnish Shelf. It's been found to "exert anti-inflammatory effects on airway responses" in cases of allergic asthma and broncheoalveolar inflammation. One study conducted in 2004 found Hemlock Varnish Shelf extract to posses liver protective properties and be anti-fibrotic.

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Variations of ganoderma within the same species as well as the growth substrate and environmental conditions all the way through to preparation of the ganoderma tea or extract can have a substantial effect on the medicinal value of the product. Microscopic Features: Spores 9-11 x 6-8; more or less elliptical, sometimes with a truncated end; usually appearing roughened even at lower magnifications. Additionally, it has whitish, rather than brownish flesh. Otherwise it is recognized, like ganoderma lucidum, by its varnished, reddish cap and stem.

Phylogenetic analysis of ganodermahas begun to better differentiate between many closely related species of ganoderma; This mushroom is closely related to ganoderma lucidum and is virtually indistinguishable from that species. However, ganoderma tsugae is partial to conifers--especially hemlock. Ecology: Saprobic on decaying conifer logs and stumps (especially hemlock wood); growing alone or in groups; annual; producing "a soft wet whitish or straw-colored cellulose-destroying decay of the wood" when young, and later a "network of cracks filled with white mycelium" with "numerous black dots throughout the wood" widely distributed in North America. A "wound area covered by SACCHACHITIN completely healed by 21 days, while that covered with cotton gauze did not." ganoderma lucidum is found on hardwood stumps and logs (very rarely on conifers), and has brownish flesh. ganoderma oregonense is a conifer lover of the Pacific Northwest and New Mexico; it has larger spores and a much larger fruiting body (up to one meter across!).