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With Ganoderma there is still an ongoing scientific debate as to which species of Ganoderma have the most medicinal properties.

Much of the therapeutic benefits are the same as those of the Common Reishi (Ganoderma lucidum), which is the oldest used medicinal mushroom in Traditional Chinese Medicine with a 2,000 year history. Stem: Sometimes absent, but more commonly present; 3-14 cm long; up to 3 cm thick; twisted; equal or irregular; varnished and colored like the cap; often distinctively angled away from one side of the cap. Variations of Ganoderma within the same species as well as the growth substrate and environmental conditions all the way through to preparation of the Ganoderma tea or extract can have a substantial effect on the medicinal value of the product.

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In the case of extracting the polysaccharides in Ganoderma tsugae, a hot water extraction or tea can be very effective; however, to best extract the triterpenoids present in G. tsugae it is best to use an alcohol or alcohol/glycerin extraction method. Polyporus tsugae is a former name. Ganoderma tsugae, also known as Hemlock varnish shelf, is a flat polypore mushroom of the genus Ganoderma.

Cap: 5-30 cm; at first irregularly knobby or elongated, but by maturity more or less fan-shaped; with a shiny, varnished surface often roughly arranged into lumpy "zones"; red to reddish brown when mature; when young often with zones of bright yellow and white toward the margin; occasionally with bluish tints. Pore Surface: White, becoming dingy brownish in age; usually bruising brown; 4-6 tiny (nearly invisible to the naked eye) circular pores per mm; tubes to 2 cm deep. As with the Common Reishi, Hemlock Varnish Shelf extract appears to be immunomodulatory - meaning that it will adjust the immune system up or down depending on what is needed. It helps strengthen a weak immune system, but will calm an over-active immune system in cases of inflammation or autoimmune conditions. Ganoderma tsugae, also known as Hemlock varnish shelf, is a flat polypore mushroom of the genus Ganoderma.