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As with the Common Reishi, Hemlock Varnish Shelf extract appears to be immunomodulatory - meaning that it will adjust the immune system up or down depending on what is needed. It helps strengthen a weak immune system, but will calm an over-active immune system in cases of inflammation or autoimmune conditions. Flesh: Whitish; fairly soft when young, but soon tough. Hemlock Varnish Shelf extract has also been tested for its antitumor properties with promising results. In particular lung cancer and breast cancer 816have responded favorably in scientific research. It was also shown in one study to help prevent cancer metastasis.

Hemlock Varnish Shelf (Ganoderma tsugae) is the local variety of Reishi for eastern United States. It is common on Hemlock trees throughout the Appalachian range. The study applied several DNA techniques and found that, while Ganoderma tsugae and Ganoderma lucidum do appear to separate with some methods, the picture is unclear enough that further study is required before reliable conclusions can be drawn. Like G. lucidum, G. tsugae is said to have medicinal properties. A "wound area covered by SACCHACHITIN completely healed by 21 days, while that covered with cotton gauze did not." One of the most novel uses of Hemlock Varnish Shelf is as a skin substitute during wound healing. The skin substitute material, commercially sold as Sacchachitin, has been proven in numerous studies to promote and speed up skin healing. It has been observed that "rapid wound healing" takes place when covered by Sacchachitin as compared to regular gauze.

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A "wound area covered by SACCHACHITIN completely healed by 21 days, while that covered with cotton gauze did not." Hemlock Varnish Shelf is not limited to the U.S., though, and plenty of Asian research has been conducted specifically on this species of Reishi. Like Ganoderma lucidum, Ganoderma tsugae is non-poisonous but generally considered inedible, due to its solid woody nature; however, making ganoderma teas and extacts from its fruiting bodies is an excellent way make use of the medicinal compounds present in Ganoderma tsugae.

Like G. lucidum, G. tsugae is said to have medicinal properties. Microscopic Features: Spores 9-11 x 6-8; more or less elliptical, sometimes with a truncated end; usually appearing roughened even at lower magnifications. Like G. lucidum, G. tsugae is said to have medicinal properties. Spore Print: Brown. Ecology: Saprobic on decaying conifer logs and stumps (especially hemlock wood); growing alone or in groups; annual; producing "a soft wet whitish or straw-colored cellulose-destroying decay of the wood" when young, and later a "network of cracks filled with white mycelium" with "numerous black dots throughout the wood" widely distributed in North America.